- Here is a response to "refute" some of the criticism regarding the value of these scientific studies. Even when the nuances of these studies are explained by the researchers or their representatives, we still have to wonder at their value. While any insanity can be represented in such a fashion to seem rational we must ask ourselves - irrespective of how interesting the results may be - do these explanations justify these kinds of monetary outlays that have gone on for decades? Outlays that seem to me to amount to not much more than academic welfare! We now know that between 80% and 90 % of all studies are incapable of being replicated.We now know in medical research “80 percent of non-randomized studies (by far the most common type) turn out to be wrong, as do 25 percent of supposedly gold-standard randomized trials, and as much as 10 percent of the platinum-standard large randomized trials. The article spelled out his belief that researchers were frequently manipulating data analyses, chasing career-advancing findings rather than good science, and even using the peer-review process—in which journals ask researchers to help decide which studies to publish—to suppress opposing views. “You can question some of the details of John’s calculations, but it’s hard to argue that the essential ideas aren’t absolutely correct,” says Doug Altman, an Oxford University researcher who directs the Centre for Statistics in Medicine.”
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Showing posts with label Study Replication Failure. Show all posts
Showing posts with label Study Replication Failure. Show all posts
Monday, October 27, 2014
Coburn releases his final government Wastebook
Outgoing Sen. Tom Coburn’s final rendition of his
government Wastebook was released this week, chronicling $25 billion worth of
wasteful spending on 100 “silly, unnecessary, and low priority projects.” “Washington
politicians are more focused on their own political futures than the future of
our country,” Coburn declares in the introduction of the publication. “And with
no one watching over the vast bureaucracy, the problem again isn’t just what
Washington isn’t
doing, but what it is
doing.” The lawmaker’s 182-page report provides example of government’s
wasteful use of taxpayer dollars at all levels, pointing out examples
everywhere from the Pentagon and Veterans Affairs Department to the National
Science Foundation. Here are just a few examples of the sort of waste Coburn highlights:
At some point these rationalizations must be recognized for what they are.
Wednesday, October 22, 2014
Most published medical research is FALSE — 85% of research funding WASTED, says Stanford study
Here’s the study.
Most published medical research is false! In 2005, in a landmark paper viewed well over a million times, John Ioannidis explained in PLOS Medicine why most published research findings are false. To coincide with PLOS Medicine’s 10th anniversary he responds to the challenge of this situation by suggesting how the research enterprise could be improved.
Most published medical research is false! In 2005, in a landmark paper viewed well over a million times, John Ioannidis explained in PLOS Medicine why most published research findings are false. To coincide with PLOS Medicine’s 10th anniversary he responds to the challenge of this situation by suggesting how the research enterprise could be improved.
Research, including medical research, is subject to a
range of biases which mean that misleading or useless work is sometimes pursued
and published while work of value is ignored. The risks and rewards of academic
careers, the structures and habits of peer reviewed journals, and the way
universities and research institutions are set up and governed all have
profound effects on what research scientists undertake, how they choose to do
it and, ultimately, how patients are treated. Perverse incentives can lead
scientists to waste time producing and publishing results which are wrong or
useless. Understanding these incentives and altering them provides a potential
way for drastically re-shaping research to improve in medical knowledge.........“The achievements of science are amazing yet the majority
of research effort is currently wasted,” asserts Ioannidis. He calls for
testing interventions to improve the structure of scientific research, and
doing so with the rigor normally reserved for testing drugs or hypotheses......To Read More.....
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