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De Omnibus Dubitandum - Lux Veritas

Showing posts with label Conclusions in search of data. Show all posts
Showing posts with label Conclusions in search of data. Show all posts

Thursday, November 17, 2022

2022 Ivermectin Research Study Shows Modern Medical Research Can Be Propaganda, Not Science

Medical research is supposed to be non-biased and professional to insulate legitimate scientific inquiry from personal and financial interests.  The recently published “Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients with Mild to Moderate Covid-19” shows the consequences of erosion of scientific integrity by political and financial biases.

The study, performed between June 2021 and February 2022, concluded that Ivermectin was no better than placebo (sugar pills) for treating mild to moderate Covid-19 illness in outpatients.[i]  Touted as the definitive protocol to silence Ivermectin promoters, the article was published in the American Medical Association’s journal JAMA on 21 October 2022.  Without explanation, the AMA did not allow online comments on the publication.  The media predictably hyped the article and simultaneously continued to criticize the drug, something it had done since early 2020.  CNBC published “Ivermectin – a drug once touted as a Covid treatment by Conservatives – doesn’t improve recovery much, clinical trial finds” 3 days after the publication was released online.

The second-in-command of the trial, Dr David Boulware, has shown contempt for Ivermectin before, during, and after the study.  The Star-Tribune interviewed him on June 13, 2022.

“Ivermectin is not an effective therapy for COVID-19 at this dose and duration, regardless of what the people promoting or selling ivermectin say," said Dr. David Boulware, a U infectious disease researcher who oversaw the design of ACTIV-6 as co-chair of its protocol committee. "This is now the second very large trial to show no benefit of ivermectin." 

Boulware said he expects ivermectin proponents to dismiss the latest results because of the lower dosage, but that they are "moving the goalpost" because he consulted with some of them at the outset of ACTIV-6 in early 2021 and they supported the dosage at that time.”  Front Line Covid-19 Critical Care Alliance (FLCCC), one of the largest proponents of ivermectin, disagreed and released a June 2022 paper stating the trial used too low of a dose too late in the course.  

This trial used lower doses and shorter durations of treatment that were not being used by Ivermectin prescribers.  Worse, the Ivermectin treatments were begun after the known peak viral load in patients.  It is well known that anti-virals must be started earlier.  Flu medication (within 2 days or less) and Paxlovid (within 5 days or less).  As a practicing ER physician, most of my covid treatments were begun within 2-3 days of symptom onset, not the 6-day lag time in the trial.  The delay is critical to understanding the drug effects and raises the question if the researchers intentionally delayed treatment for so long to minimize effects of the investigated drug.  With the authors’ obvious bias, this is entirely plausible...................To Read More....

Monday, January 4, 2021

January 4, 2021 By Brian C.Joondeph, MD 

Imagine changing the rules in the middle of a football game. The halftime score is 14-12, the Raiders scoring two touchdowns while the Broncos kicked four field goals. In the second half the rules change with field goals worth seven points and touchdowns only three points. Suddenly the Broncos are ahead 28-6. Absurd isn’t it?

That’s what is happening with the reporting of COVID deaths versus vaccine deaths, the media and medical establishment now defining deaths far differently in order to push their agenda of COVID bad, vaccine good.

COVID deaths don’t distinguish between death with COVID versus death from COVID. Early in the pandemic, Dr Deborah Birx said as much:............To Read More....

 

Friday, April 22, 2011

Observations From the Back Row: 4-22-11

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“De Omnibus Dubitandum”

We live in a time when great efforts have been made, and continue to be made, to falsify the record of the past and to make history a tool of propaganda; when governments, religious movements, political parties, and sectional groups of every kind are busy rewriting history as they wish it to have been, as they would like their followers to believe that it was. - Islam Bernard Lewis', historian

Energy saving light bulbs 'contain cancer causing chemicals' Fears have been reignited about the safety of energy saving light bulbs after a group of scientists warned that they contain cancer causing chemicals. …..Their report advises that the bulbs should not be left on for extended periods, particularly near someone’s head, as they emit poisonous materials when switched on. The bulbs are already widely used in the UK following EU direction to phase out traditional incandescent lighting by the end of this year.

The Department for the Environment insists the bulbs are safe, despite the fact that they contain small amounts of mercury which would leak out if the glass was broken.

My Take – Whoa….Safe in spite of the “small amounts of mercury”. I thought there was “no safe level of mercury”. What we have here is another stupid greenie idea imposed on the public by a bunch of stupid bureaucrats given unbridled authority by a bunch of unprincipled politicians. So…..why isn’t the Precautionary Principle being applied here? In the E.U. the (PP) has become almost sacrosanct. Why no outrage from the greenies and their acolytes in government and the media? Viv Forbes really is right. The green movement really is “an unholy alliance of environmental scaremongers, funds-seeking academics, sensation-seeking media, vote-seeking politicians and profit-seeking vested interests.” Besides….the stupid really are dangerous.

Genetic breakthrough may stop spread of malaria The development is seen as a potential breakthrough in preventing the spread of one of the world's most dangerous diseases. Malaria kills up to a million people a year, mostly children living in Africa where the disease is endemic, and strikes down a further 500 million victims who fall seriously ill.

A decade ago, scientists created the first GM mosquitoes but their potential use in stemming the transmission of malaria has been stymied by the theoretical inability of the engineered insects to out-compete the non-GM mosquitoes living in the wild that actually harbour the blood parasite.

However, a new study has shown that it is possible for GM mosquitoes to rapidly pass on malaria-blocking genes to wild mosquitoes with the help of a second gene that spreads the GM trait within the sperm-producing cells of male mosquitoes.

The plan is to physically attach the synthetic gene, called the homing endonuclease gene, to an anti-malaria gene and insert the entire genetic construct into male GM mosquitoes released into the wild. The endonuclease gene should then ensure that nearly all the sperm cells produced by these GM males will carry the anti-malaria trait into the next generation of mosquitoes.

Malaria in numbers
• 500 million new cases of malaria are reported worldwide each year.
• 1 million deaths are caused by malaria each year, the majority in Africa.
• 57 countries are registered as 'malaria-endemic', with the disease posing a threat to human life.
• 200,000 people die of malaria each year in India.
• 2 million cases of malaria were reported in Pakistan after last October's floods.
• 1.3 per cent rate at which malariacan decrease gross domestic product in countries with high disease rates.
• 765 million people in sub-Saharan Africa are said to be at risk from malaria, according to the World Health Organisation.
My Take - First off…..if bed nets by themselves were so great this wouldn’t be happening. Secondly, if bed nets and pyrethroidal pesticides were so great together this would be happening. Thirdly, if this can really be done in the wild this will be a major blessing for humanity. The problem with all of these types of solutions is the delivery system. Can this take place in the wild? We can only hope.

Now…..what will the greenies do? They hate anything that is GM. If everything they stand for and promote is “for the children”, as they claim, they will wholeheartedly support this? If they do however, this will completely undermine all of their arguments about genetic modification. If they stand against this it will expose them for the irrational misanthropic people they really are. This will be interesting to watch.


Anti-pesticide activists exploit poor kids While it’s not surprising that children from the inner city and Latino farmworker communities might perform slightly less well than average American children on development tests, anti-pesticide activists can make it news if they can link that performance to pesticides. And so they have tried.

Environmental Health Perspectives published three studies today purporting to link prenatal exposure to organophosphate pesticides with substandard performance on development tests by the aforementioned groups of children.
I’m sure than the well-known anti-pesticide activist-researchers involved (Brenda Eskenazi, Frederica Perera and Mary Wolff) expect to overwhelm the media with their message by releasing all three studies at once, but here are the underlying fatal flaws common to all three studies:
• Even accepting the study results at face value for the sake of argument, the test score deficiencies are insignificant. There is no meaningful developmental difference between a child who scores a 100 on an IQ test vs. one who scores a 101.4.
• Childhood development is a complex, multifactorial phenomenon, which these researchers have magically reduced down to blood levels of pesticide metabolites. While most reasonable people would point to the children’s general plight in Lower Social-economia as the likely cause of whatever development issues they may have, Eskenazi, Perera and Wolff have conjured up a superficial statistical analyses to advance their personal financial and political agendas as well as the bureaucratic and political agenda of their funding agency, the anti-pesticide EPA.
• There is no known biological mechanism that explains how legal exposures to pesticides might lead to developmental problems.

My Take - This whole business of IQ is another one of those ethereal "findings" from these studies that are conclusions in search of data. The first time I came across this was during the Litulis Kilgore days. Kilgore was operating an illegal pest control business using methyl parathion (MP), one of the most toxic liquid pesticides developed for exclusive use in agriculture. In sunlight it would breakdown within 24 to 48 hours. It was never meant to be used in homes or businesses.

These people have been followed by the Center for Disease Control for years. What did they find? They “think” that MP “may” have caused an IQ problem. Why only a maybe? Because the findings weren’t consistent! It appeared to be true in one group and not in another. There is a reason for that. It isn’t true. IQ is a complicated and subjective thing and trying to pin this on pesticides is another article of faith by the green movement. It was only two months ago that they were claiming that piperonyl butoxide, a synergist mixed with pesticides also caused it.

We need to get this. These studies are all conclusions in search of data.


"The time has come," the Walrus said,
"To talk of many things:
Of shoes, and ships, and sealing wax -
Of cabbages and kings,
And why the sea is boiling hot,
And whether pigs have wings."

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