By Jo Nova
John Ioannidis paints a picture of a vast hive of researchers all pushed to publish short papers that are mostly a waste of time. The design is bad, the results useless (even when meta-collated with other badly designed studies). Basically, humankind is pouring blood, sweat and tears into spinning wheels in medicine — just paper churn. Most papers will never help a patient. Ioannidis wants rigor – full registration before the study, full transparency afterwards, fewer studies over all, but with better design. Astonishingly, fully 85% of what is spent on clinical trials is wasted. ... Read more
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